Burns are tissue injuries resulting from direct contact with flames
Burns are tissue injuries resulting from direct contact with flames, liquids, gases or hot surfaces, caustic chemicals, electricity or radiation. Explains the General Council of Official Colleges of Pharmacists, a patient with a burn should be evaluated a number of factors determine the severity of symptoms and therefore treatment. The skin is the most frequently damaged, which compromises its role as a barrier to lesionesy infections, as well as the regulator of body temperature. Before a burn patient should be evaluated a number of factors determine the severity of symptoms and therefore treatment.
The burn involves the destruction of cells in the affected area. The loss of keratin and lipids, which act as a barrier to evaporation, promotes water loss and thus loss of body heat. Moreover, the loss of the integrity of the skin, provides the possibility of infection.
The direct action of heat encourages the release of the vessels of vasoactive substances (histamine, prostaglandins) that increase vascular permeability, leading to local heat, flushing, and edema. This situation may lead to detachment of the epidermis and blisters. The dead tissue will fall off and replaced by new tissue.
When it is very superficial burns, the residual elements of the dermis regenerate the skin quickly, leaving no scars or permanent sequelae.
In severe cases, there is the cessation of blood flow in the burned area due to clots that block the capillaries. In this case, can cause the loss of the defense mechanisms of the area, inability to access the white blood cells and antibiotics administered by a systemic route. Also significantly hinders the restoration of damaged tissue.